The Chinese anti-inflammatory and immunosuppressive herbal remedy Tripterygium wilfordii Hook F

X Tao, P Lipsky (2000) The Chinese anti-inflammatory and immunosuppressive herbal remedy Tripterygium wilfordii Hook F Rheum Dis Clin North Am (IF: 3) 26(1) 29-50, viii

Abstract

Various preparations of Tripterygium wilfordii Hook F (TwHF) have been used in the treatment of a number of autoimmune and inflammatory diseases since the 1960s. Accumulated data from the clinical trials suggest efficacy of this treatment in a number of rheumatic diseases, including rheumatoid arthritis and systemic lupus erythematosus. Studies on the relationship of the chemical components of TwHF and its immunosuppressive and anti-inflammatory effects suggest that diterpenoid compounds with epoxide groups account for the therapeutic effects of this herbal remedy. This herbal remedy is therefore a unique and powerful alternative therapy for autoimmune and inflammatory diseases.

Links

http://www.ncbi.nlm.nih.gov/pubmed/10680192
http://dx.doi.org/10.1016/s0889-857x(05)70118-6

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