Functional domains, structural variations and pathogen interactions of MCP, DAF and CR1

D Hourcade, M Liszewski, M Krych-Goldberg, J Atkinson (2000) Functional domains, structural variations and pathogen interactions of MCP, DAF and CR1 Immunopharmacology 49(1-2) 103-16

Abstract

The Regulators of Complement Activation (RCA) are a fascinating group of proteins that play important roles in innate and acquired immunity. In this review, we examine structure-function aspects of three membrane-bound RCA proteins and discuss the unique impact of their genetic organization on their evolution.

Links

http://www.ncbi.nlm.nih.gov/pubmed/10904110
http://dx.doi.org/10.1016/s0162-3109(00)80296-9

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