Stetson, Cui, Montague, Eagleman (2006) Motor-sensory recalibration leads to an illusory reversal of action and sensation Neuron 51(5) 651-9

Abstract

To judge causality, organisms must determine the temporal order of their actions and sensations. However, this judgment may be confounded by changing delays in sensory pathways, suggesting the need for dynamic temporal recalibration. To test for such a mechanism, we artificially injected a fixed delay between participants' actions (keypresses) and subsequent sensations (flashes). After participants adapted to this delay, flashes at unexpectedly short delays after the keypress were often perceived as occurring before the keypress, demonstrating a recalibration of motor-sensory temporal order judgments. When participants experienced illusory reversals, fMRI BOLD signals increased in anterior cingulate cortex/medial frontal cortex (ACC/MFC), a brain region previously implicated in conflict monitoring. This illusion-specific activation suggests that the brain maintains not only a recalibrated representation of timing, but also a less-plastic representation against which to compare it.

为了判断因果关系,有机体必须确定其行为和感觉的时间顺序。然而,这种判断可能会因感觉通路的延迟变化而混淆,这表明需要进行动态时间重新校准。为了测试这种机制,我们在参与者的动作(按键)和随后的感觉(闪烁)之间人为地注入固定的延迟。在参与者适应这种延迟之后,在按键之后经常感觉到在按键之前发生意外的短暂延迟时闪烁,表明运动感觉时间顺序判断的重新校准。当参与者经历虚幻的逆转时,fMRI BOLD信号在前扣带皮层/内侧额叶皮层(ACC / MFC)中增加,这是一个先前涉及冲突监测的大脑区域。这种特定于错觉的激活表明,大脑不仅维持了时间的重新校准表示,而且还保留了较少的塑性表示来比较它。

Links

http://www.ncbi.nlm.nih.gov/pubmed/16950162
http://dx.doi.org/10.1016/j.neuron.2006.08.006

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