Care and management of the infant of the HIV-1-infected mother

Paintsil, Andiman (2007) Care and management of the infant of the HIV-1-infected mother Semin Perinatol (IF: 3.2) 31(2) 112-23

Abstract

Mother-to-child transmission of the human immunodeficiency virus continues to be a major global health problem. The pediatric HIV-1 epidemic is fueled by HIV-1 infection in women of childbearing age with vertical transmission in utero or at the time of birth. In resource-rich countries, the birth of an infected child is a sentinel health event signaling a chain of missed opportunities and barriers to prevention. Because the fate and ultimate HIV-infection status of the baby is inextricably linked to the infection status of the mother and her general state of well-being, we provide in this review: 1) background and state-of-the-art management guidelines for optimum maternal care; 2) strategies to minimize the risk of vertical transmission of HIV; and 3) recommendations for managing infants born to HIV-infected women. These are discussed under four case scenarios that obstetric and pediatric providers frequently encounter in their practices.

Links

http://www.ncbi.nlm.nih.gov/pubmed/17462496
http://dx.doi.org/10.1053/j.semperi.2007.02.007

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