Primary Nocardia meningitis in a patient without a predisposing condition: case report and review of the literature

Hussam Al Soub, Mona Almaslamani, Jameela Al Khuwaiter, Yasser El Deeb, Mohammed Khatab (2007) Primary Nocardia meningitis in a patient without a predisposing condition: case report and review of the literature Scand J Infect Dis (IF: 2.2) 39(8) 737-41

Abstract

A case of primary Nocardia meningitis in a patient without a predisposing condition is presented and 4 other reported cases are reviewed. The presenting features were fever, headache, altered consciousness, and neck stiffness. Cerebrospinal fluid examination (CSF) revealed hypoglycorrhachia (<40 mg/dl), elevated protein (>100 mg/dl), and pleocytosis with predominant neutrophils in all patients. Culture of CSF was positive for Nocardia in 4 of the 5 patients. Mortality was 50%. Diagnosis was frequently delayed and this probably contributed to the high mortality. Compared with Nocardia meningitis in association with a predisposing condition, primary Nocardia meningitis without a predisposing condition has similar clinical features and outcome.

Links

http://www.ncbi.nlm.nih.gov/pubmed/17654355
http://dx.doi.org/10.1080/00365540701199873

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