beta(1-3)Glucanosyltransferase Gel4p is essential for Aspergillus fumigatus

Amandine Gastebois, Thierry Fontaine, Jean-Paul Latgé, Isabelle Mouyna (2010) beta(1-3)Glucanosyltransferase Gel4p is essential for Aspergillus fumigatus Eukaryot Cell (IF: 3) 9(8) 1294-8

Abstract

The beta(1-3)glucanosyltransferase GEL family of Aspergillus fumigatus contains 7 genes, among which only 3 are expressed during mycelial growth. The role of the GEL4 gene was investigated in this study. Like the other Gelps, it encodes a glycosylphosphatidylinositol (GPI)-anchored protein. In contrast to the other beta(1-3)glucanosyltransferases analyzed to date, it is essential for this fungal species.

Links

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2918925
http://www.ncbi.nlm.nih.gov/pubmed/20543062
http://dx.doi.org/10.1128/EC.00107-10

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