Well differentiated thyroid carcinoma: current treatment
Byrd, Yawn, Wilhoit, Sora, Meyers, Fernandes, Day (2012) Well differentiated thyroid carcinoma: current treatment Curr Treat Options Oncol (IF: 4.7) 13(1) 47-57Abstract
Well differentiated thyroid carcinoma (WDTC) is a relatively common malignancy accounting for an estimated 37,000 thousand cases in the United States in 2009 [1]. WDTC also has a generally high 5 year survival rate that correlates with age. Papillary thyroid carcinoma (PTC) greater than 1 cm is best managed by total thyroidectomy. Thyroid lobectomy and isthmusectomy may be adequate for unifocal PTC less than 1 cm in patients without negative prognostic factors. Central compartment and possible lateral neck dissections should be performed when nodal metastases are present in the respective nodal basins. Post-operatively, radioactive iodine ablation with (131)I followed by thyroid stimulating hormone (TSH) suppression is indicated in certain patients to improve locoregional control and reduce recurrence.
Links
http://www.ncbi.nlm.nih.gov/pubmed/22234582http://dx.doi.org/10.1007/s11864-011-0173-1
