Arene ruthenium(II) Complexes: The Promising Chemotherapeutic Agent in Inhibiting the Proliferation, Migration and Invasion
Zheng, Wu, Ding, Mei (2016) Arene ruthenium(II) Complexes: The Promising Chemotherapeutic Agent in Inhibiting the Proliferation, Migration and Invasion Mini Rev Med Chem (IF: 3) 16(10) 796-803Abstract
Arene ruthenium(II) complexes have been widely investigated as one of the most promising candidates in chemotherapy because of their low toxicity and high inhibiting activity against the proliferation, invasion, migration, and angiogenesis of various tumors in vitro and in vivo. This review highlights the recent developments in different chemical types of arene Ru(II) complexes, as well as their biological activity and underlying mechanisms. The sustained efforts in this aspect of arene Ru(II) complexes would be essential in developing novel anti-tumor agents in the near future.
Links
http://www.ncbi.nlm.nih.gov/pubmed/26423698http://dx.doi.org/10.2174/1389557515666151001142159
