Heart Failure with Recovered EF and Heart Failure with Mid-Range EF: Current Recommendations and Controversies
Unkovic, Basuray (2018) Heart Failure with Recovered EF and Heart Failure with Mid-Range EF: Current Recommendations and Controversies Curr Treat Options Cardiovasc Med (IF: 0.8) 20(4) 35Abstract
This review explores key features and potential management controversies in two emerging populations in heart failure: heart failure with recovered ejection fraction (HF-recovered EF) and heart failure with mid-range ejection fraction (HFmrEF).While HF-recovered EF patients have better outcomes than heart failure with reduced ejection fraction (HFrEF), they continue to have symptoms, persistent biomarker elevations, and abnormal outcomes suggesting a continued disease process. HFmrEF patients appear to have features of HFrEF and heart failure with preserved ejection fraction (HFpEF), but have a high prevalence of ischemic heart disease and may represent a transitory phase between the HFrEF and HFpEF. Management strategies have insufficient data to warrant standardization at this time. HF-recovered EF and HFmrEF represent new populations with unmet needs and expose the pitfalls of an EF basis for heart failure classification.
Links
http://www.ncbi.nlm.nih.gov/pubmed/29616374http://dx.doi.org/10.1007/s11936-018-0628-9
