Preclinical development of a high affinity α-synuclein antibody, MEDI1341, that can enter the brain, sequester extracellular α-synuclein and attenuate α-synuclein spreading in vivo
Schofield, Irving, Calo, Bogstedt, Rees, Nuccitelli, Narwal, Petrone, Roberts, Brown, Cusdin, Dosanjh, Lloyd, Dobson, Gurrell, Fraser, McFarlane, Rockenstein, Spencer, Masliah, Spillantini, Tan, Billinton, Vaughan, Chessell, Perkinton (2019) Preclinical development of a high affinity α-synuclein antibody, MEDI1341, that can enter the brain, sequester extracellular α-synuclein and attenuate α-synuclein spreading in vivo Neurobiol Dis (IF: 6.1) 132 104582Links
http://www.ncbi.nlm.nih.gov/pubmed/31445162http://dx.doi.org/10.1016/j.nbd.2019.104582