Extracorporeal cytokine adsorption as therapeutic option for immune effector cell-associated neurotoxicity syndrome

Buhlmann, Rom, Schweiger, Schneidawind, David (2025) Extracorporeal cytokine adsorption as therapeutic option for immune effector cell-associated neurotoxicity syndrome Neurol Sci (IF: 2.4) 46(1) 479-481

Abstract

With the rising number of patients receiving chimeric antigen receptor T-cells, the treatment of this therapy's complications is of growing concern to intensivists and neurologists. We used extracorporeal cytokine adsorption as an add-on therapy in a patient suffering from immune effector cell-associated neurotoxicity syndrome. Interleukin-6 level, which as a readily available parameter is generally used to evaluate course of disease, was rapidly reduced using this method. The patient made a full recovery and is still in hematological remission.© 2024. The Author(s).

Links

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11698748
http://www.ncbi.nlm.nih.gov/pubmed/39417926
http://dx.doi.org/10.1007/s10072-024-07812-1

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