Insertional mutagenesis in transgenic mice
Rijkers, Peetz, Rüther (1994) Insertional mutagenesis in transgenic mice Transgenic Res (IF: 2.7) 3(4) 203-15Abstract
Increasing numbers of transgenic mouse lines have resulted in several dozens of mutants created by insertional mutagenesis. The advantages of different vector systems and the problems associated with the analysis of mutations and the cloning of the affected genes are discussed in this review.
Links
http://www.ncbi.nlm.nih.gov/pubmed/7920737http://dx.doi.org/10.1007/BF02336773
