NotI jumping and linking clones as a tool for genome mapping and analysis of chromosome rearrangements in different tumors
Zabarovsky, Kashuba, Gizatullin, Winberg, Zabarovska, Erlandsson, Domninsky, Bannikov, Pokrovskaya, Kholodnyuk, Petrov, Zakharyev, Kisselev, Klein (1996) NotI jumping and linking clones as a tool for genome mapping and analysis of chromosome rearrangements in different tumors Cancer Detect Prev (IF: 0) 20(1) 1-10Abstract
Long-range restriction site maps are of central importance for mapping the human genome. The use of clones from linking and jumping libraries for genome mapping offers a promising alternative to the laborious procedures used up until now. In the present review, this research field is analyzed with particular emphasis on the implementation of a shot-gun sequencing strategy for genome mapping and the use of NotI linking clones for analysis of rearrangements in tumors and tumor cell lines.
